Product Description
Pentaerythrityl Tetraisostearate, also known as Pentaerythritol Tetraisostearate or PTIS, is a branched-chain fatty acid ester formed from pentaerythritol and isostearic acid. With the molecular formula C77H148O8 and a molecular weight of approximately 1201.99 g/mol, it is a high-molecular-weight ester used primarily as a functional ingredient in personal care formulations.
Its structure contains four ester groups and multiple branched hydrocarbon chains. These features contribute to its oil-based character and make it useful when a formulation requires a rich emollient that helps reduce the dry or rough feel of skin. Depending on the formulation, it can also contribute to product spreadability, surface lubrication, and a smoother after-feel.
In cosmetic development, Pentaerythrityl Tetraisostearate may be considered for creams, lotions, balms, color cosmetics, and other oil-containing products. Its performance depends on the overall ingredient system, concentration, processing conditions, and desired sensory profile. It should therefore be evaluated in the finished formulation rather than selected on ingredient identity alone.
For purchasing and quality control, confirm the exact INCI name, CAS number, appearance, applicable specification, and batch documentation. Commercial grades may differ in properties and performance; the supplier’s current technical data sheet and certificate of analysis should be used to verify product-specific values.

Chemical Properties
| Property | Details |
|---|---|
| Product Name | Pentaerythrityl Tetraisostearate |
| INCI Name | Pentaerythrityl Tetraisostearate |
| CAS Number | 62125-22-8 |
| EC Number | 263-423-1 |
| Synonyms | Pentaerythritol Tetraisostearate; Pentaerythityl Tetraisostearate; PTIS |
| Molecular Formula | C77H148O8 |
| Molecular Weight | Approximately 1201.99 g/mol |
| Chemical Class | Branched-chain fatty acid tetraester |
| Chemical Structure | Tetraester of pentaerythritol and isostearic acid |
| Appearance | Typically described as an oil or viscous oily material; confirm against the supplied grade |
| Water Solubility | Insoluble in water |
| Functional Properties | Emollient; skin-conditioning agent; may contribute to lubrication and formulation texture |
| Typical Application Area | Skin care, color cosmetics, and other personal care formulations |
| Storage | Follow the supplier’s technical data sheet and safety data sheet; keep the container tightly closed under the recommended storage conditions |
Product Applications
1. Skin Care Creams and Lotions
Pentaerythrityl Tetraisostearate can be incorporated into selected cream and lotion systems to improve emolliency, reduce a dry skin feel, and support a smoother sensory finish. Compatibility should be assessed within the complete emulsion.
2. Lip Balms and Lip Care Products
In oil-rich lip care formulations, this ester may help provide lubrication, a smooth application feel, and a conditioning finish. The suitable use level depends on the desired texture, gloss, and overall formula balance.
3. Color Cosmetics
It can be evaluated in products such as foundations, concealers, and other oil-containing makeup formulations where emolliency and spreadability are important. Its contribution to pigment wetting and finished-product performance should be verified through formulation testing.
4. Balms and Anhydrous Formulations
The ingredient may be suitable for selected balms, salves, and oil-based skin care products that require an emollient component. Formulators should assess its interaction with waxes, oils, and other structuring ingredients.
5. Specialty Personal Care Formulations
Pentaerythrityl Tetraisostearate can be considered in other personal care products where a rich ester emollient is desired. Final selection should account for sensory requirements, stability, compatibility, and applicable cosmetic regulations.

FAQ
Q1: What is Pentaerythrityl Tetraisostearate?
Pentaerythrityl Tetraisostearate is a branched-chain fatty acid tetraester made from pentaerythritol and isostearic acid. It is used mainly as an emollient and skin-conditioning ingredient in cosmetic formulations.
Q2: What is the CAS number of Pentaerythrityl Tetraisostearate?
Its CAS number is 62125-22-8. This number helps distinguish the ingredient from other pentaerythritol esters.
Q3: Is Pentaerythrityl Tetraisostearate the same as Pentaerythritol Tetraisostearate?
These names are used as synonyms for the ingredient associated with CAS 62125-22-8. The CAS number and exact product specification should be checked when confirming material identity.
Q4: What is the main function of Pentaerythrityl Tetraisostearate in cosmetics?
Its primary role is emolliency and skin conditioning. Depending on the formulation, it can also contribute to lubrication, spreadability, and a smoother skin feel.
Q5: Is Pentaerythrityl Tetraisostearate soluble in water?
No. It is water-insoluble and is generally evaluated in oil-containing or anhydrous formulation systems. Its compatibility with other ingredients should be confirmed through formulation testing.
Q6: Which cosmetic products can contain Pentaerythrityl Tetraisostearate?
Potential applications include skin creams, lotions, lip care products, balms, and selected color cosmetics. Suitability depends on the intended product, formulation design, and applicable regulations.
Q7: What should buyers verify before purchasing Pentaerythrityl Tetraisostearate?
Check the CAS number, INCI name, appearance, specification, packaging, and batch documentation. For cosmetic manufacturing, also confirm the documentation and regulatory information required for the intended market.
