Product Description
Sodium Gualenate, also known as Sodium Guaiazulene Sulfonate, is an organic sodium salt derived from a sulfonated azulene structure. Identified by CAS No. 6223-35-4, this compound combines an aromatic azulene-based framework with a sulfonate group, giving it a distinctive chemical identity and characteristic blue coloration.
As a specialized chemical raw material, Sodium Gualenate CAS 6223-35-4 is associated with pharmaceutical formulation development and research involving mucosal-care preparations. Its chemical structure and reported biological relevance make it a material of interest for selected pharmaceutical research applications. Suitability for any finished medicinal product must be established through appropriate quality, safety, efficacy, and regulatory assessments.
Sodium Gualenate is commonly described as a blue to dark blue powder or crystalline material. Its handling and storage requirements deserve particular attention because exposure to light, oxygen, moisture, and elevated temperatures may affect material quality. Actual stability depends on the supplied grade, packaging, and storage environment.
For manufacturers, research laboratories, and pharmaceutical ingredient buyers, important selection criteria include assay, identity, water content, impurity profile, physical form, and applicable pharmacopeial or internal specifications. Buyers should also distinguish Sodium Gualenate from related azulene compounds and confirm that the CAS number matches the intended material.

Chemical Properties
| Property | Details |
|---|---|
| Product Name | Sodium Gualenate |
| Synonyms | Sodium Guaiazulene Sulfonate; Guaiazulenesulfonate Sodium; Sodium Azulene Sulfonate |
| CAS Number | 6223-35-4 |
| Molecular Formula | C15H17NaO3S |
| Molecular Weight | 300.35 g/mol |
| Chemical Class | Organic Sodium Salt; Azulene Sulfonate Derivative |
| Appearance | Blue to Dark Blue Powder or Crystalline Solid |
| Melting Point | Approximately 98°C (reported reference value) |
| Solubility | Reported soluble in DMSO; solubility in water and other solvents should be confirmed for the specified grade |
| Physical Form | Powder or Crystalline Material |
| Water Content | May vary by grade; confirm the specification for anhydrous or hydrated material |
| Light Sensitivity | Protect from prolonged exposure to light |
| Storage Conditions | Follow the manufacturer's current storage instructions; use suitable, tightly closed packaging and protect from light |
| Chemical Stability | Stability may be affected by light, air exposure, moisture, and temperature |
Property Note: The values above describe commonly reported characteristics of Sodium Gualenate. Hydration state, water content, assay, and physical form can vary among supplied grades. Confirm the exact material identity and release criteria using the relevant analytical specification and batch documentation.
Product Applications
1. Pharmaceutical Formulation Research
Sodium Gualenate is associated with pharmaceutical research involving formulations designed for gastrointestinal and mucosal applications. Its suitability for a specific dosage form depends on the intended use, quality grade, formulation compatibility, and applicable regulatory requirements.
2. Gastrointestinal Formulation Development
The compound has been investigated in the context of gastric and gastrointestinal preparations. Research and formulation teams should establish its suitability for a particular product through appropriate technical data, published evidence, and regulatory review rather than assuming a therapeutic effect from the raw material alone.
3. Oral and Mucosal Care Formulations
Sodium Gualenate may be evaluated in the development of selected oral or mucosal-care preparations where the material is permitted and the relevant grade is appropriate. Finished-product compatibility, stability, safety, and local regulatory requirements must be assessed before use.
4. Pharmaceutical Ingredient and Analytical Research
The defined chemical identity of Sodium Gualenate makes it suitable for analytical characterization, reference comparisons, and research into azulene-derived compounds. Laboratories may evaluate identity, assay, water content, impurity profile, and stability using methods appropriate to the material.
5. Specialty Chemical Research
Sodium Gualenate can also be used in research involving sulfonated azulene derivatives and their physicochemical properties. Such work may include solubility assessment, stability studies, and investigation of the compound's behavior under different formulation conditions.

FAQ
Q1: What is Sodium Gualenate?
Sodium Gualenate is a sodium salt of a sulfonated azulene-derived compound, also known as Sodium Guaiazulene Sulfonate. Its CAS number is 6223-35-4.
Q2: What are the molecular formula and molecular weight of Sodium Gualenate?
The commonly listed molecular formula is C15H17NaO3S, and the molecular weight is approximately 300.35 g/mol for the anhydrous formula.
Q3: What does Sodium Gualenate look like?
It is commonly described as a blue to dark blue powder or crystalline solid. The exact appearance depends on the grade and physical form supplied.
Q4: How should Sodium Gualenate be stored?
Follow the supplier's product-specific storage instructions. Appropriate packaging and protection from prolonged light exposure, excessive moisture, and unsuitable temperatures can help maintain material quality.
Q5: What should buyers verify before ordering?
Confirm the CAS number, assay, water content, impurity limits, physical form, packaging, and applicable quality documentation. For pharmaceutical use, verify the required grade and regulatory suitability for the intended market.
For sourcing inquiries, specify the required grade and intended application so the relevant product specifications and quality documents can be reviewed.
